… Design, synthesis, and in vitro hMAO-B inhibitory evaluation of some 1-methyl-3, 5-diphenyl-4,
5-dihydro-1H-pyrazoles. Bioorg Med Chem Lett 2013; 23 (18): 5128-30. …

… were designed and synthesized to be evaluated as selective human MAO-B inhibitors. A …
The compounds were tested for their inhibitory activities on both human MAO-A and B. All …

… This inhibitory versatility is related to the plasticity of the hMAO-B active site cavity. As
described above, the cavity can hold small inhibitors such as isatin and tranylcypromine, or cavity-…

… al designed and synthesized a series of 1-methyl-3,5-diphenyl4,5-dihydro-1H-pyrazoles, and
evaluated for their inhibitory … hMAO-B inhibitors. In particular, derivative 51 showed greater …

… and design of reversible and selective inhibitors for MAO-A or MAO-B isoforms has been
emphasized in ongoing research. This review … ve izatin-hMAO-B enzim kompleksinde izatindeki …